Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 13/20 | 1.00 |
| ▸ | CYP11B2 | P19099 | 13/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.67 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552675 | 0.80 | CYP19A1 (1.00) | CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL8506 | 0.73 | CYP19A1 (0.69) | CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL29651625 | 0.73 | CYP19A1 (0.69) | CYP11B1CYP11B2CYP19A1CYP17A1 | |
| SCHEMBL24046790 | 0.72 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1SIGMAR1 | |
| SCHEMBL7305898 | 0.71 | SIGMAR1 (0.77) | CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL7298240 | 0.70 | SIGMAR1 (0.75) | CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL24046842 | 0.70 | PPARG (0.78) | CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL7299989 | 0.70 | SIGMAR1 (0.75) | CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL17237763 | 0.70 | SIGMAR1 (0.75) | CYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL5695477 | 0.70 | PPARG (0.63) | CYP11B1CYP11B2CYP19A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | claimed |
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |