Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21477182 | 0.86 | MAOB (0.41) | P4HTMMAOBGAAMAPTMAOA | |
| SCHEMBL21464583 | 0.84 | L3MBTL1 (0.47) | P4HTMMAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL19023188 | 0.83 | P4HTM (0.54) | P4HTMMAOBGAAMAPTMAOA | |
| SCHEMBL16343085 | 0.80 | TSHR (0.50) | MAOBMAPTBCHECA1CA2 | |
| SCHEMBL18768538 | 0.78 | P4HTM (0.46) | P4HTMMAOBGAAMAPTMAOA | |
| SCHEMBL2648020 | 0.77 | MAOB (0.61) | P4HTMMAOBGAAMAPTMAOA | |
| SCHEMBL30362841 | 0.77 | MAOB (0.61) | P4HTMMAOBGAAMAPTMAOA | |
| SCHEMBL31011207 | 0.76 | P4HTM (0.50) | P4HTMMAOBGAAMAPTMAOA | |
| SCHEMBL29273695 | 0.76 | P4HTM (0.50) | P4HTMMAOBGAAMAPTMAOA | |
| Hydrochloric Acid SCHEMBL1330115 | 0.76 | MAOB (0.59) | P4HTMMAOBGAAMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2090575-B1 | Processes and intermediates for the preparation of N4-phenyl-quinazoline-4-amine derivatives | ARRAY BIOPHARMA INC (US) | 2011-04-27 | — | — | EP | disclosed |