SCHEMBL29273695

SCHEMBL29273695

ON=CNc1ccc(OCc2ccccc2)cn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 1/20 0.50
GCK P35557 1/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C19 P33261 2/20 0.45
LMNA P02545 2/20 0.45
PTGS1 P23219 1/20 0.45
SLC6A2 P23975 1/20 0.45
PTGS2 P35354 1/20 0.45
SLC6A3 Q01959 1/20 0.45
HIF1A Q16665 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
MAOB P27338 2/20 0.42
BCHE P06276 1/20 0.42
GSK3B P49841 1/20 0.42
BACE1 P56817 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31011207 1.00 P4HTM (0.50) P4HTMGCKCYP1A2CYP2C19LMNA
SCHEMBL1552689 0.76 P4HTM (0.54) P4HTMGCKCYP1A2CYP2C19LMNA
SCHEMBL19023188 0.76 P4HTM (0.54) P4HTMGCKCYP1A2CYP2C19LMNA
SCHEMBL18768538 0.71 P4HTM (0.46) P4HTMGCKCYP1A2CYP2C19LMNA
SCHEMBL7784532 0.70 FDPS (0.52) P4HTMGCKCYP1A2CYP2C19LMNA
SCHEMBL13535008 0.69 P4HTM (0.60) P4HTMCYP1A2CYP2C19LMNAPTGS1
SCHEMBL27211083 0.69 P4HTM (0.52) P4HTMGCKCYP1A2CYP2C19MEN1
SCHEMBL189964 0.68 RAB9A (0.71) CYP1A2CYP2C19LMNAPTGS1SLC6A2
SCHEMBL189965 0.68 RAB9A (0.71) CYP1A2CYP2C19LMNAPTGS1SLC6A2
SCHEMBL2297148 0.68 RAB9A (0.71) CYP1A2CYP2C19LMNAPTGS1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118206548-A Synthesis method of [1,2,4] triazolo [1,5-a ] pyridin-6-ol 江苏工程职业技术学院 2024-06-18 CN claimed
CN-118206548-A Synthesis method of [1,2,4] triazolo [1,5-a ] pyridin-6-ol 江苏工程职业技术学院 2024-06-18 CN disclosed