Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.64 |
| ▸ | NAAA | Q02083 | 5/20 | 0.59 |
| ▸ | MIF | P14174 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | BACH1 | O14867 | 1/20 | 0.42 |
| ▸ | MAFK | O60675 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11854374 | 0.91 | — | — | |
| SCHEMBL331092 | 0.87 | TRPA1 (0.68) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL28836397 | 0.84 | TRPA1 (0.67) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL11859234 | 0.82 | NAAA (0.69) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL11727275 | 0.82 | NAAA (0.69) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL25332310 | 0.78 | TRPA1 (1.00) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL5352877 | 0.78 | TRPA1 (1.00) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL3123984 | 0.78 | TRPA1 (1.00) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL2679812 | 0.78 | TRPA1 (1.00) | TRPA1NAAAMIFGSK3BKEAP1 | |
| SCHEMBL1020887 | 0.78 | TRPA1 (1.00) | TRPA1NAAAMIFGSK3BKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013166421-A1 | MELANOMA CHEMOPREVENTION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2013-11-07 | — | — | WO | disclosed |