Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 9/20 | 0.51 |
| ▸ | GABRD | O14764 | 9/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.51 |
| ▸ | GABRE | P78334 | 9/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528008 | 0.91 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15528315 | 0.91 | TNKS (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8932 | 0.87 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9273 | 0.84 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8856 | 0.84 | GABRA1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15528119 | 0.84 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13726082 | 0.84 | AR (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8632 | 0.80 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15528004 | 0.79 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8108 | 0.79 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844647-A1 | PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2- (1 -HYDROXY- ALKYL) - CHROMEN - 4 - ONE DERIVATIVES AND THEIR USE IN PREPARING PHARMACEUTICALS | Rhizen Pharmaceuticals S.A. (CH) | 2015-03-11 | — | — | EP | claimed |
| WO-2013164801-A1 | PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2- (1 -HYDROXY- ALKYL) - CHROMEN - 4 - ONE DERIVATIVES AND THEIR USE IN PREPARING PHARMACEUTICALS | RHIZEN PHARMACEUTICALS SA (CH) | 2013-11-07 | — | — | WO | claimed |
| EP-2870157-A1 | SELECTIVE PI3K DELTA INHIBITORS | Rhizen Pharmaceuticals S.A. (CH) | 2015-05-13 | — | — | EP | disclosed |
| EP-2844647-A1 | PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2- (1 -HYDROXY- ALKYL) - CHROMEN - 4 - ONE DERIVATIVES AND THEIR USE IN PREPARING PHARMACEUTICALS | Rhizen Pharmaceuticals S.A. (CH) | 2015-03-11 | — | — | EP | disclosed |
| WO-2014006572-A1 | SELECTIVE PI3K DELTA INHIBITORS | RHIZEN PHARMACEUTICALS SA (CH) | 2014-01-09 | — | — | WO | disclosed |
| WO-2013164801-A1 | PROCESS FOR PREPARATION OF OPTICALLY PURE AND OPTIONALLY SUBSTITUTED 2- (1 -HYDROXY- ALKYL) - CHROMEN - 4 - ONE DERIVATIVES AND THEIR USE IN PREPARING PHARMACEUTICALS | RHIZEN PHARMACEUTICALS SA (CH) | 2013-11-07 | — | — | WO | disclosed |