SCHEMBL1552856

SCHEMBL1552856

CCCCNCCC(C)CCCN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CA12 O43570 3/20 0.41
CA2 P00918 3/20 0.41
CA4 P22748 3/20 0.41
CA6 P23280 3/20 0.41
CA5A P35218 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
CA5B Q9Y2D0 3/20 0.41
CASP2 P42575 2/20 0.41
F13A1 P00488 2/20 0.41
CYP1A2 P05177 2/20 0.41
ALOX15 P16050 2/20 0.41
THPO P40225 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29027621 0.92 CA12 (0.46) TSHRCA12CA2CA4CA6
SCHEMBL18893457 0.90 TSHR (0.44) TSHRCA12CA2CA4CA6
SCHEMBL3699607 0.89 CA12 (0.43) TSHRCA12CA2CA4CA6
SCHEMBL9807783 0.89 RELA (0.45) TSHRCA12CA2CA4CA6
SCHEMBL10596435 0.88 CA12 (0.43) TSHRCA12CA2CA4CA6
SCHEMBL18629873 0.86 ALDH1A1 (0.46) TSHRCA12CA2CA4CA6
SCHEMBL23869885 0.83 TSHR (0.50) TSHRALDH1A1LMNADNM1
SCHEMBL2353027 0.83 CA12 (0.50) TSHRCA12CA2CA4CA6
SCHEMBL4317793 0.83 TSHR (0.46) TSHRCA2MEN1KMT2AALDH1A1
SCHEMBL19933018 0.82 CA12 (0.44) TSHRCA12CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778842-B2 Sample lysis and coating of reaction surface QIAGEN GMBH (DE) 2014-07-15 US claimed
EP-1856168-B1 SAMPLE LYSIS AND COATING OF REACTION SURFACE QIAGEN GMBH (DE) 2011-04-27 EP claimed
US-20080299557-A1 Sample Lysis and Coating of Reaction Surface QIAGEN GMBH (DE) 2008-12-04 US claimed
US-20210388221-A1 WATERBORNED LIGHT RADIATION POLYURETHANE MIXED POLYESTER POLYMER COATING SYSTEM SOLARIS TECHNOLOGY LTD. (GB) 2021-12-16 US disclosed
US-11008471-B2 Waterborne light radiation absorbing polyurethane mixed polyester polymer coating system Solaris Technology Ltd (GB) 2021-05-18 US disclosed
US-20160257824-A1 WATERBORNE LIGHT RADIATION ABSORBING POLYURETHANE MIXED POLYESTER POLYMER COATING SYSTEM CLEAR TECHNOLOGY HOLDINGS, LLC (US) 2016-09-08 US disclosed
US-8778842-B2 Sample lysis and coating of reaction surface QIAGEN GMBH (DE) 2014-07-15 US disclosed
US-8084132-B1 Antimicrobial coatings World Pharmaceutical Trust (US) 2011-12-27 US disclosed
EP-1856168-B1 SAMPLE LYSIS AND COATING OF REACTION SURFACE QIAGEN GMBH (DE) 2011-04-27 EP disclosed
US-20080299557-A1 Sample Lysis and Coating of Reaction Surface QIAGEN GMBH (DE) 2008-12-04 US disclosed
EP-1856168-A1 SAMPLE LYSIS AND COATING OF REACTION SURFACE Qiagen GmbH (DE) 2007-11-21 EP disclosed
WO-2006084650-A1 SAMPLE LYSIS AND COATING OF REACTION SURFACE QIAGEN GMBH (DE) 2006-08-17 WO disclosed
EP-0700945-B1 Water-based, solvent-free or low voc, two-component polyurethane coatings HART R H LABS INC (US) 2002-11-20 EP disclosed
US-5693703-A Water-based, solvent-free or low VOC, two-component polyurethane coatings R. E. HART LABS, INC. (US) 1997-12-02 US disclosed
US-5508340-A Water-based, solvent-free or low voc, two-component polyurethane coatings R. E. HART LABS, INC. (US) 1996-04-16 US disclosed
EP-0700945-A1 Water-based, solvent-free or low voc, two-component polyurethane coatings R.E. HART LABS, INC. (US) 1996-03-13 EP disclosed
EP-0210022-A2 Storage stable, one part polyorganosiloxane compositions DOW CORNING CORPORATION (US) 1987-01-28 EP disclosed