Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IL18 | Q14116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23322893 | 0.81 | MEN1 (0.59) | MAPTLMNAHTTKMT2APOLB | |
| SCHEMBL10963561 | 0.81 | KMT2A (0.54) | MAPTSAE1UBA2LMNAHTT | |
| SCHEMBL20941638 | 0.81 | SAE1 (0.62) | MAPTSAE1UBA2PAX8LMNA | |
| SCHEMBL11068773 | 0.80 | MAPT (0.43) | MAPTLMNAHTTCA12CA1 | |
| SCHEMBL694247 | 0.80 | CYP1A1 (0.53) | MAPTLMNATSHRHTTCA12 | |
| SCHEMBL8688893 | 0.80 | SAE1 (0.57) | MAPTSAE1UBA2PAX8LMNA | |
| SCHEMBL2933871 | 0.78 | KMT2A (0.63) | MAPTLMNAHTTKMT2AMEN1 | |
| SCHEMBL4835086 | 0.78 | MEN1 (0.65) | MAPTLMNAHTTKMT2APOLB | |
| SCHEMBL1532371 | 0.78 | POLB (0.63) | MAPTLMNAHTTCA12CA1 | |
| SCHEMBL572726 | 0.78 | GAA (0.56) | MAPTHTTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590332-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | University of Delhi (IN) | 2005-11-02 | — | — | EP | claimed |
| WO-2004063170-A1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND ITS DERIVATIONS | UNIVERSITY OF DELHI (IN) | 2004-07-29 | — | — | WO | claimed |
| EP-1590332-B1 | A PROCESS FOR THE SYNTHESIS OF BISBENZIMIDAZOLES AND THEIR DERIVATIVES. | UNIV DELHI (IN) | 2011-04-27 | — | — | EP | disclosed |