Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364611 | 0.83 | ALDH1A1 (0.46) | LMNAKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15364482 | 0.77 | LMNA (0.50) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL15364655 | 0.77 | LMNA (0.50) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL27992951 | 0.75 | ALDH1A1 (0.54) | LMNAKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15364656 | 0.70 | LMNA (0.43) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL15364055 | 0.70 | LMNA (0.46) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL22362216 | 0.68 | LMNA (0.69) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL15364277 | 0.67 | ALDH1A1 (0.48) | LMNAKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14288483 | 0.66 | HDAC1 (0.52) | LMNAKDM4EHTTSMN1; SMN2ALOX12 | |
| SCHEMBL25429589 | 0.65 | LMNA (0.60) | LMNAKDM4EHTTSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844678-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | Bridgestone Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013166124-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | WO | disclosed |