Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534311 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL23509591 | 0.83 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL22491782 | 0.83 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL25600200 | 0.81 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1TDP1SMN1; SMN2LMNA | |
| SCHEMBL1932493 | 0.79 | KDM4E (0.40) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1932163 | 0.79 | KDM4E (0.40) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1932001 | 0.79 | KDM4E (0.40) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5720935 | 0.78 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL15709827 | 0.78 | FFAR1 (0.50) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL15709624 | 0.78 | FFAR1 (0.50) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852573-A1 | N-[3-(2-CARBOXYETHYL)PHENYL]PIPERIDIN-1-YLACETAMIDE DERIVATIVES AND USE THEREOF AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | Bayer Pharma Aktiengesellschaft (DE) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174736-A1 | N-[3-(2-CARBOXYETHYL)PHENYL]PIPERIDIN-1-YLACETAMIDE DERIVATIVES AND USE THEREOF AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-11-28 | — | — | WO | disclosed |