Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 7/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.48 |
| ▸ | PRKCG | P05129 | 2/20 | 0.48 |
| ▸ | PRKCB | P05771 | 2/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.48 |
| ▸ | PRKCA | P17252 | 2/20 | 0.48 |
| ▸ | PRKCH | P24723 | 2/20 | 0.48 |
| ▸ | PRKCI | P41743 | 2/20 | 0.48 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533684 | 0.83 | DYRK1A (0.47) | PIK3CGPIK3CBDYRK1ACLK4MEN1 | |
| SCHEMBL15533647 | 0.80 | PIK3CG (0.45) | PIK3CGPIK3CBMEN1RAB9AKMT2A | |
| SCHEMBL15533883 | 0.80 | MAPK8 (0.45) | PIK3CGMEN1RAB9AKMT2AMAPT | |
| SCHEMBL15533672 | 0.79 | MAPT (0.48) | CLK4MEN1RAB9AKMT2AMAPT | |
| SCHEMBL14088787 | 0.77 | JAK2 (0.59) | PIK3CGPIK3CBDYRK1ACLK4MEN1 | |
| SCHEMBL4903233 | 0.77 | JAK2 (0.65) | PIK3CGPIK3CBDYRK1ACLK4MEN1 | |
| SCHEMBL15533545 | 0.76 | DYRK1A (0.49) | PIK3CGPIK3CBDYRK1ACLK4MEN1 | |
| SCHEMBL15533771 | 0.76 | DYRK1A (0.54) | PIK3CGPIK3CBDYRK1ACLK4MEN1 | |
| SCHEMBL3381635 | 0.75 | FYN (0.50) | DYRK1AMEN1RAB9AKMT2AMAPT | |
| SCHEMBL13279659 | 0.75 | MEN1 (0.52) | PIK3CGPIK3CBMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |