Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | PRKCG | P05129 | 2/20 | 0.46 |
| ▸ | PRKCB | P05771 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | PRKCH | P24723 | 2/20 | 0.46 |
| ▸ | PRKCI | P41743 | 2/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533545 | 0.87 | DYRK1A (0.49) | DYRK1ACLK4MAPTKMT2AGAA | |
| SCHEMBL15533865 | 0.85 | SYK (0.53) | DYRK1ACLK4MAPTKMT2AMEN1 | |
| SCHEMBL15533951 | 0.83 | PIK3CG (0.50) | DYRK1ACLK4MAPTKMT2AGAA | |
| SCHEMBL15534348 | 0.81 | MEN1 (0.46) | DYRK1ACLK4MAPTKMT2AGAA | |
| SCHEMBL15534241 | 0.80 | CLK1 (0.63) | DYRK1ACLK4MAPTABL1BCR | |
| SCHEMBL15533965 | 0.80 | SYK (0.51) | DYRK1ACLK4MAPTKMT2AGAA | |
| SCHEMBL15533631 | 0.80 | ABL1 (0.46) | CLK4MAPTKMT2AGAAMEN1 | |
| SCHEMBL14742731 | 0.80 | MEN1 (0.73) | MAPTKMT2AGAAMEN1RAB9A | |
| SCHEMBL15534009 | 0.78 | MAPT (0.48) | DYRK1ACLK4MAPTGAAZAP70 | |
| SCHEMBL15533704 | 0.77 | ABL1 (0.47) | DYRK1ACLK4MAPTZAP70EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |