SCHEMBL15533957

SCHEMBL15533957

NCc1c(I)cc(I)cc1I

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 1/20 0.41
▸ HTR2A P28223 1/20 0.32
▸ ERN1 O75460 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18242830 0.73 TTR (0.43) TTRERN1
SCHEMBL31488013 0.72 HTR1D (0.37) TTRHTR2A
SCHEMBL28647290 0.71 TTR (0.41) TTRERN1
SCHEMBL9001912 0.71 TTR (0.41) TTRERN1
SCHEMBL7592654 0.71 TTR (0.48) TTRERN1
SCHEMBL28879948 0.71 TAAR1 (0.42) HTR2A
SCHEMBL18243170 0.71 TTR (0.41) TTRERN1
SCHEMBL17161237 0.70 TTR (0.36) TTR
SCHEMBL18243159 0.69 TTR (0.39) TTRERN1
SCHEMBL17750340 0.67 TTR (0.43) TTRHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12087564-B2 Tuned synthetic dendrimer calibrants for mass spectrometry THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2024-09-10 — — US disclosed
US-20220384167-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2022-12-01 — — US disclosed
US-11217435-B2 Tuned synthetic dendrimer calibrants for mass spectrometry THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2022-01-04 — — US disclosed
US-20200090917-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2020-03-19 — — US disclosed
US-10347476-B2 Tuned synthetic dendrimer calibrants for mass spectrometry THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2019-07-09 — — US disclosed
US-20150132854-A1 Tuned Synthetic Dendrimer Calibrants for Mass Spectrometry THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2015-05-14 — — US disclosed
WO-2013177223-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2013-11-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11217435-B2 Tuned synthetic dendrimer calibrants for mass spectrometry SRMS, SRM, DNMT1 TTR 1483/4885HTR2A 4652/4885ERN1 4434/4885
US-20220384167-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY SRMS, SRM, DNMT1 TTR 1483/4885HTR2A 4652/4885ERN1 4434/4885
US-10347476-B2 Tuned synthetic dendrimer calibrants for mass spectrometry SRMS, SRM, DNMT1 TTR 1610/4885HTR2A 4711/4885ERN1 4467/4885
US-20200090917-A1 TUNED SYNTHETIC DENDRIMER CALIBRANTS FOR MASS SPECTROMETRY SRMS, SRM, DNMT1 TTR 1483/4885HTR2A 4652/4885ERN1 4434/4885
US-12087564-B2 Tuned synthetic dendrimer calibrants for mass spectrometry SRMS, SRM, DNMT1 TTR 1483/4885HTR2A 4652/4885ERN1 4434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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