Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | ABL1 | P00519 | 9/20 | 0.43 |
| ▸ | BCR | P11274 | 8/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15534396 | 0.99 | TRPV1 (0.47) | TRPV1ABL1BCRJAK2MAPT | |
| Hydrochloric Acid SCHEMBL15533549 | 0.99 | TRPV1 (0.47) | TRPV1ABL1BCRJAK2MAPT | |
| Sulfuric Acid SCHEMBL15533134 | 0.94 | ABL1 (0.47) | TRPV1ABL1BCRJAK2MAPT | |
| SCHEMBL15534503 | 0.93 | ABL1 (0.48) | TRPV1ABL1BCRJAK2TAS2R14 | |
| SCHEMBL15533761 | 0.91 | ABL1 (0.44) | TRPV1ABL1BCRJAK2MAPT | |
| SCHEMBL15534267 | 0.89 | TRPV1 (0.56) | TRPV1ABL1BCRJAK2MAPT | |
| SCHEMBL15534109 | 0.87 | ABL1 (0.42) | TRPV1ABL1BCRJAK2MAPT | |
| SCHEMBL15533815 | 0.86 | TRPV1 (0.48) | TRPV1ABL1BCRJAK2MAPT | |
| SCHEMBL15533228 | 0.85 | ABL1 (0.44) | TRPV1ABL1BCRJAK2MAPT | |
| SCHEMBL15534259 | 0.85 | TRPV1 (0.57) | TRPV1ABL1BCRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |