Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 9/20 | 0.44 |
| ▸ | BCR | P11274 | 8/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534267 | 0.90 | TRPV1 (0.56) | TRPV1MAPTTP53ABL1BCR | |
| SCHEMBL15534101 | 0.86 | TRPV1 (0.47) | TRPV1MAPTTP53ABL1BCR | |
| SCHEMBL15533871 | 0.86 | TP53 (0.51) | TRPV1MAPTTP53ABL1BCR | |
| Hydrochloric Acid SCHEMBL15533549 | 0.85 | TRPV1 (0.47) | TRPV1MAPTTP53ABL1BCR | |
| Bromide SCHEMBL15534396 | 0.85 | TRPV1 (0.47) | TRPV1MAPTTP53ABL1BCR | |
| SCHEMBL15534259 | 0.84 | TRPV1 (0.57) | TRPV1ABL1BCR | |
| SCHEMBL15534449 | 0.83 | TRPV1 (0.47) | TRPV1MAPTTP53ABL1BCR | |
| SCHEMBL15534464 | 0.82 | ABL1 (0.46) | TRPV1MAPTTP53ABL1BCR | |
| SCHEMBL15533969 | 0.82 | CYP1A1 (0.48) | TP53ABL1BCRSYKGRM5 | |
| Sulfuric Acid SCHEMBL15533134 | 0.82 | ABL1 (0.47) | TRPV1MAPTTP53ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |