Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.41 |
| ▸ | BCR | P11274 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533762 | 0.93 | ABL1 (0.44) | ABL1BCRTRPV1MAPK1TNNI3K | |
| SCHEMBL15534505 | 0.88 | ABL1 (0.46) | ABL1BCRTRPV1MAPK1TNNI3K | |
| SCHEMBL15534109 | 0.86 | ABL1 (0.42) | ABL1BCRMEN1KMT2APTGS2 | |
| SCHEMBL15534503 | 0.82 | ABL1 (0.48) | ABL1BCRMEN1KMT2ATRPV1 | |
| Sulfuric Acid SCHEMBL15533134 | 0.81 | ABL1 (0.47) | ABL1BCRTRPV1MAPK1TYK2 | |
| SCHEMBL15534290 | 0.81 | ABL1 (0.46) | ABL1BCRBRAFTRPV1MAPK1 | |
| SCHEMBL15534101 | 0.80 | TRPV1 (0.47) | ABL1BCRMEN1KMT2ATRPV1 | |
| Hydrochloric Acid SCHEMBL15533549 | 0.79 | TRPV1 (0.47) | ABL1BCRMEN1KMT2ATRPV1 | |
| Bromide SCHEMBL15534396 | 0.79 | TRPV1 (0.47) | ABL1BCRMEN1KMT2ATRPV1 | |
| SCHEMBL15533761 | 0.78 | ABL1 (0.44) | ABL1BCRTRPV1MAPK1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |