Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.44 |
| ▸ | BCR | P11274 | 7/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534205 | 0.93 | ABL1 (0.41) | ABL1BCRTRPV1CCNT1CDK9 | |
| SCHEMBL15534505 | 0.90 | ABL1 (0.46) | ABL1BCRTRPV1USP2CYP1A2 | |
| SCHEMBL15533761 | 0.85 | ABL1 (0.44) | ABL1BCRTAS2R14TRPV1KMO | |
| Sulfuric Acid SCHEMBL15533134 | 0.84 | ABL1 (0.47) | ABL1BCRTAS2R14TRPV1KMO | |
| SCHEMBL15534503 | 0.83 | ABL1 (0.48) | ABL1BCRTAS2R14TRPV1KMO | |
| SCHEMBL15534101 | 0.83 | TRPV1 (0.47) | ABL1BCRTAS2R14TRPV1JAK2 | |
| SCHEMBL15534290 | 0.82 | ABL1 (0.46) | ABL1BCRTAS2R14TRPV1USP2 | |
| Hydrochloric Acid SCHEMBL15533549 | 0.82 | TRPV1 (0.47) | ABL1BCRTAS2R14TRPV1JAK2 | |
| Bromide SCHEMBL15534396 | 0.82 | TRPV1 (0.47) | ABL1BCRTAS2R14TRPV1JAK2 | |
| SCHEMBL15533871 | 0.78 | TP53 (0.51) | ABL1BCRTAS2R14TRPV1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |