Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15557985 | 0.81 | QDPR (0.37) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1367319 | 0.81 | MAPT (0.38) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL15534537 | 0.80 | NAMPT (0.52) | CNR1 | |
| SCHEMBL15556551 | 0.80 | CNR1 (0.63) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17844399 | 0.79 | MAPT (0.37) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL2266251 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL28595070 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL21994832 | 0.78 | CNR1 (0.43) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL2241959 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL17255325 | 0.77 | HPGD (0.42) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852584-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174780-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2013-11-28 | — | — | WO | disclosed |