SCHEMBL1553490

SCHEMBL1553490

O=C(O)OCCCCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.65
SMN1; SMN2 Q16637 3/20 0.57
NPC1 O15118 1/20 0.57
RECQL P46063 1/20 0.57
RAB9A P51151 1/20 0.57
FFAR1 O14842 1/20 0.56
TDP1 Q9NUW8 2/20 0.55
MAPT P10636 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
HDAC3 O15379 1/20 0.53
MAPK1 P28482 1/20 0.53
ADRA1A P35348 1/20 0.53
HDAC4 P56524 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HDAC1 Q13547 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53
HDAC8 Q9BY41 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21681731 0.98 LMNA (0.62) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL21681726 0.98 LMNA (0.62) LMNASMN1; SMN2NPC1RECQLRAB9A
Bicarbonate SCHEMBL27813134 0.98 LMNA (0.62) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL9370334 0.98 LMNA (0.62) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL21681730 0.98 LMNA (0.62) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL21681727 0.98 LMNA (0.62) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1554317 0.94 LMNA (0.72) LMNASMN1; SMN2NPC1RECQLRAB9A
Hydrochloric Acid SCHEMBL11851895 0.92 LMNA (0.70) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL982156 0.88 LMNA (0.65) LMNASMN1; SMN2NPC1RECQLRAB9A
SCHEMBL1836828 0.86 LMNA (0.62) LMNASMN1; SMN2NPC1RECQLRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
US-11174337-B2 Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-16 US disclosed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN disclosed
CN-108395374-B Process for producing diaryl carbonate 旭化成株式会社 2021-03-30 CN disclosed
US-20200048405-A1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE POLYMER AND ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-02-13 US disclosed
EP-3105215-A1 DIALKYL CARBONATES, METHODS FOR THEIR PRODUCTION AND USE Huntsman Petrochemical LLC (US) 2016-12-21 EP disclosed
CN-105102422-A Method for producing isocyanate ASAHI KASEI CHEMICALS CORP 2015-11-25 CN disclosed
WO-2015123486-A1 DIALKYL CARBONATES, METHODS FOR THEIR PRODUCTION AND USE HUNTSMAN PETROCHEMICAL LLC (US) 2015-08-20 WO disclosed
EP-2788314-A2 A PROCESS FOR PRODUCING AROMATIC CARBONATES Shell Internationale Research Maatschappij B.V. (NL) 2014-10-15 EP disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
US-5659065-A CHEMICAL INTERMEDIATES FOR MEDICINAL ACTIVE AGENTS NOVARTIS CORPORATION (US) 1997-08-19 US disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
EP-0678500-A1 Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors CIBA-GEIGY AG (CH) 1995-10-25 EP disclosed
US-5436242-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof for inhibiting blood platelet aggregation SANKYO COMPANY, LIMITED (JP) 1995-07-25 US disclosed
EP-0602242-A1 BENZISOXAZOLE COMPOUND AND USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1994-06-22 EP disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed
US-4556737-A ANTIALLERGENS, TREATMENT OF ASTHMA AND RHINITIS TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1985-12-03 US disclosed