Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21681731 | 1.00 | LMNA (0.62) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL21681730 | 1.00 | LMNA (0.62) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL21681727 | 1.00 | LMNA (0.62) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL21681726 | 1.00 | LMNA (0.62) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL1553490 | 0.98 | LMNA (0.65) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| Bicarbonate SCHEMBL27813134 | 0.96 | LMNA (0.62) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL1554317 | 0.92 | LMNA (0.72) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11851895 | 0.90 | LMNA (0.70) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL1839278 | 0.89 | LMNA (0.62) | LMNAMAPTRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL1836828 | 0.89 | LMNA (0.62) | LMNAMAPTRXFP1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803992-B | Isocyanate composition and method for producing isocyanate polymer | 旭化成株式会社 | 2022-05-24 | — | — | CN | disclosed |
| CN-109843963-B | Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer | 旭化成株式会社 | 2022-05-13 | — | — | CN | disclosed |
| US-11174337-B2 | Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2021-11-16 | — | — | US | disclosed |
| CN-107963982-B | Polyisocyanate composition and isocyanate polymer composition | 旭化成株式会社 | 2021-11-12 | — | — | CN | disclosed |
| US-20200048405-A1 | ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE POLYMER AND ISOCYANATE POLYMER | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-02-13 | — | — | US | disclosed |
| CN-102471244-B | Process for producing N-substituted carbamate, process for producing isocyanate using the N-substituted carbamate, and composition for transporting and storing N-substituted carbamate containing N-substituted carbamate and aromatic hydroxy compound | ASAHI CHEMICAL CORP | 2014-09-24 | — | — | CN | disclosed |
| CN-102105439-A | Method for producing N-substituted carbamate and method for producing isocyanate using the N-substituted carbamate | ASAHI KASEI CHEMICALS CORP (JP) | 2011-06-22 | — | — | CN | disclosed |
| CN-1224001-A | Process for preparation of carbonates and polycarbonates | MONSANTO CO (US) | 1999-07-28 | — | — | CN | disclosed |
| US-5344934-A | Reaction of carbon dioxide and amine in aprotic solvents | MONSANTO COMPANY (US) | 1994-09-06 | — | — | US | disclosed |