Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GNRHR | P30968 | 2/20 | 0.46 |
| ▸ | LGMN | Q99538 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534658 | 0.91 | GNRHR (0.44) | MEN1KMT2AGNRHRPTGER4POLB | |
| SCHEMBL15534659 | 0.91 | GNRHR (0.44) | MEN1KMT2AGNRHRPTGER4POLB | |
| SCHEMBL15535202 | 0.79 | GNRHR (0.48) | MEN1KMT2AGNRHRPTGER4 | |
| SCHEMBL15535203 | 0.79 | GNRHR (0.48) | MEN1KMT2AGNRHRPTGER4 | |
| SCHEMBL15534936 | 0.74 | TAS2R14 (0.43) | MEN1KMT2ALGMNPOLBALDH1A1 | |
| SCHEMBL6882846 | 0.73 | MEN1 (0.46) | MEN1KMT2AGNRHRPOLBALDH1A1 | |
| SCHEMBL15158080 | 0.71 | MEN1 (0.51) | MEN1KMT2AGNRHRPOLBALDH1A1 | |
| SCHEMBL4293151 | 0.71 | MEN1 (0.53) | MEN1KMT2AGNRHRALDH1A1GAA | |
| SCHEMBL15534872 | 0.70 | CCNA2 (0.45) | GNRHR | |
| SCHEMBL15534871 | 0.70 | CCNA2 (0.45) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177349-A2 | QUINAZOLINEDIONES AS TANKYRASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |