Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534659 | 1.00 | GNRHR (0.44) | GNRHRPOLBHTR4ACHEPTGER4 | |
| SCHEMBL15534935 | 0.91 | MEN1 (0.47) | GNRHRPOLBPTGER4MEN1KMT2A | |
| SCHEMBL15535202 | 0.88 | GNRHR (0.48) | GNRHRHTR4PTGER4CNR1CNR2 | |
| SCHEMBL15535203 | 0.88 | GNRHR (0.48) | GNRHRHTR4PTGER4CNR1CNR2 | |
| SCHEMBL15534872 | 0.79 | CCNA2 (0.45) | GNRHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15534871 | 0.79 | CCNA2 (0.45) | GNRHRHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12798265 | 0.76 | ALDH1A1 (0.48) | GNRHRPOLBHTR4HDAC3HDAC4 | |
| SCHEMBL1668907 | 0.76 | ALDH1A1 (0.48) | GNRHRPOLBHTR4HDAC3HDAC4 | |
| SCHEMBL1666506 | 0.76 | ALDH1A1 (0.48) | GNRHRPOLBHTR4HDAC3HDAC4 | |
| SCHEMBL11893819 | 0.76 | ALDH1A1 (0.48) | GNRHRPOLBHTR4HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177349-A2 | QUINAZOLINEDIONES AS TANKYRASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |