Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534608 | 0.87 | MAPT (0.56) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2056118 | 0.86 | GPR119 (0.77) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL20176399 | 0.85 | LMNA (0.54) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4973566 | 0.85 | GPR119 (0.61) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28572326 | 0.84 | MAPT (0.56) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL12082170 | 0.84 | GPR119 (0.79) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30208161 | 0.84 | GPR119 (0.79) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5573222 | 0.83 | MAPT (0.76) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL15533835 | 0.83 | EGLN2 (0.57) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL31428609 | 0.83 | GPR119 (0.52) | GPR119MAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177253-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-11-28 | — | — | WO | disclosed |