Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80613 | 0.91 | DGAT1 (0.37) | DGAT1CYP4F2CYP4A11 | |
| SCHEMBL30683839 | 0.89 | NPSR1 (0.34) | DGAT1CYP4F2CYP4A11NPSR1BTK | |
| SCHEMBL6355124 | 0.87 | NPSR1 (0.33) | DGAT1CYP4F2CYP4A11NPSR1GAA | |
| SCHEMBL22927448 | 0.85 | DGAT1 (0.33) | DGAT1CYP4F2CYP4A11NPSR1BTK | |
| SCHEMBL4829842 | 0.83 | NPSR1 (0.31) | DGAT1CYP4F2CYP4A11NPSR1BTK | |
| SCHEMBL23293553 | 0.82 | CYP2C19 (0.32) | CYP4F2CYP4A11NPSR1BTK | |
| SCHEMBL4824038 | 0.82 | CYP4F2 (0.31) | CYP4F2CYP4A11NPSR1 | |
| SCHEMBL4825718 | 0.82 | NPSR1 (0.42) | DGAT1CYP4F2CYP4A11NPSR1BTK | |
| SCHEMBL7884001 | 0.80 | CYP2C19 (0.31) | CYP4F2CYP4A11 | |
| SCHEMBL27574308 | 0.80 | CYP4F2 (0.30) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | claimed |
| CN-104321311-A | Novel process for the preparation of 2-cyclopentyl-6-methoxy-isonicotinic acid | ACTELION PHARMACEUTICALS LTD | 2015-01-28 | — | — | CN | claimed |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | disclosed |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | disclosed |
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-05-14 | — | — | US | disclosed |
| EP-2861585-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | Novartis AG (CH) | 2015-04-22 | — | — | EP | disclosed |
| EP-2852575-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | Actelion Pharmaceuticals Ltd. (CH) | 2015-04-01 | — | — | EP | disclosed |
| CN-104321311-A | Novel process for the preparation of 2-cyclopentyl-6-methoxy-isonicotinic acid | ACTELION PHARMACEUTICALS LTD | 2015-01-28 | — | — | CN | disclosed |
| WO-2014033631-A1 | N-(3-PYRIDYL) BIARYLAMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2014-03-06 | — | — | WO | disclosed |
| WO-2013175388-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013175397-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | ACTELION PHARMACEUTICALS LTD (CH) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133669-A1 | NEW PROCESS FOR THE PREPARATION OF 2-CYCLOPENTYL-6-METHOXY-ISONICOTINIC ACID | IMPDH1, IMPDH2, ITPA | DGAT1 2944/4885CYP4F2 258/4885CYP4A11 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.