SCHEMBL15535405

SCHEMBL15535405

CO[Si](CCCOCC(O)CN(C(C)C)C(C)C)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.37
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.35
ABCB1 P08183 10/20 0.33
SPHK1 Q9NYA1 1/20 0.33
HSF1 Q00613 1/20 0.32
LPAR5 Q9H1C0 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
CASR P41180 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15536338 0.85 USP2 (0.38) USP2HTTHSD17B10ABCB1SPHK1
SCHEMBL9927998 0.83 HSD17B10 (0.38) USP2HTTHSD17B10SPHK1LPAR5
SCHEMBL9927994 0.83 USP2 (0.38) USP2HTTHSD17B10SPHK1LPAR5
SCHEMBL13484060 0.81 USP2 (0.40) USP2HTTHSD17B10SPHK1LPAR5
SCHEMBL61834 0.81 USP2 (0.37) USP2HTTHSD17B10SPHK1HSF1
SCHEMBL15255243 0.81 USP2 (0.37) USP2HTTHSD17B10SPHK1LPAR5
SCHEMBL61330 0.81 USP2 (0.37) USP2HTTHSD17B10SPHK1LPAR5
SCHEMBL16710535 0.81 USP2 (0.40) USP2HTTHSD17B10SPHK1LPAR5
SCHEMBL16306570 0.81 LMNA (0.45) USP2HTTHSD17B10ABCB1SPHK1
SCHEMBL15582554 0.81 USP2 (0.37) USP2HTTHSD17B10SPHK1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2852625-B1 SILANE GROUPS CONTAINING POLYMER SIKA TECH AG (CH) 2019-01-23 EP disclosed
US-9714316-B2 Polymer containing silane groups SIKA TECHNOLOGY AG (CH) 2017-07-25 US disclosed
US-20150133603-A1 POLYMER CONTAINING SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2015-05-14 US disclosed
EP-2852625-A1 POLYMER CONTAINING SILANE GROUPS Sika Technology AG (CH) 2015-04-01 EP disclosed
WO-2013174892-A1 POLYMER CONTAINING SILANE GROUPS SIKA TECHNOLOGY AG (CH) 2013-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150133603-A1 POLYMER CONTAINING SILANE GROUPS HSPH1, EHMT2, EHMT1 USP2 1815/4885HTT 484/4885HSD17B10 1393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.