SCHEMBL61834

SCHEMBL61834

CO[Si](CCCOCC(O)CN(CCC[Si](OC)(OC)OC)CCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.37
HTT P42858 1/20 0.36
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LPAR5 Q9H1C0 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HSF1 Q00613 1/20 0.31
SPHK1 Q9NYA1 1/20 0.30
CASR P41180 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60823 0.97 USP2 (0.35) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL61330 0.97 USP2 (0.37) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL15536645 0.94 KDM4E (0.42) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL15255243 0.94 USP2 (0.37) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL9928006 0.92 USP2 (0.39) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL9927994 0.92 USP2 (0.38) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL15536159 0.91 USP2 (0.35) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL62323 0.88 CASR (0.34) USP2HTTALDH1A1KDM4ELMNA
SCHEMBL14425305 0.88 USP2 (0.33) USP2HTTALDH1A1KDM4EMAPK1
SCHEMBL15582572 0.88 LMNA (0.40) USP2HTTALDH1A1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394909-B2 Silane-terminated polyurethanes with high strength and high elongation CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-03-12 US disclosed
US-8377191-B2 Surfactant-stabilized organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2013-02-19 US disclosed
US-8128748-B2 Aqueous two-component organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2012-03-06 US disclosed
US-20100234502-A1 ADHESION PROMOTER AND CURABLE RESIN COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-09-16 US disclosed
US-20090240072-A1 Mixing Device for Liquids SIKA TECHNOLOGY AG (CH) 2009-09-24 US disclosed
US-20090227710-A1 SILANE-TERMINATED POLYURETHANES WITH HIGH STRENGTH AND HIGH ELONGATION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-09-10 US disclosed
US-20090053411-A1 Surfactant-stabilized organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2009-02-26 US disclosed
US-7482420-B2 Silane-terminated polyurethanes with high strength and high elongation CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-01-27 US disclosed
US-20080314518-A1 Aqueous two-component organoalkoxysilane composition SUTTER JOLANDA 2008-12-25 US disclosed
US-20070190345-A1 Aqueous two-component organoalkoxysilane composition SIKA TECHNOLOGY AG (CH) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090053411-A1 Surfactant-stabilized organoalkoxysilane composition TST, STS, SMURF1 USP2 2546/4885HTT 442/4885ALDH1A1 4417/4885
US-20100234502-A1 ADHESION PROMOTER AND CURABLE RESIN COMPOSITION ELL, CARM1, ITGA1 USP2 1842/4885HTT 2481/4885ALDH1A1 794/4885
US-20090240072-A1 Mixing Device for Liquids SAMM50, CUL5, UBE3A USP2 788/4885HTT 1509/4885ALDH1A1 1631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.