Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 9/20 | 0.68 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.65 |
| ▸ | THRA | P10827 | 6/20 | 0.58 |
| ▸ | THRB | P10828 | 6/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808948 | 0.80 | PLK1 (0.97) | PLK1PLK3TRPA1TRPM2PLA2G1B | |
| SCHEMBL466141 | 0.79 | PLK1 (0.63) | PLK1PLK3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL13199682 | 0.78 | KDM6B (0.70) | PLK1PLK3TRPA1ALDH1A1HPGD | |
| SCHEMBL11430175 | 0.78 | PLK1 (0.66) | PLK1PLK3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11443814 | 0.78 | PLK1 (0.66) | PLK1PLK3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11432358 | 0.78 | PLK1 (0.66) | PLK1PLK3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10475728 | 0.78 | PLK1 (0.66) | PLK1PLK3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11483067 | 0.78 | PLK1 (0.66) | PLK1PLK3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11437269 | 0.78 | PLK1 (0.66) | PLK1PLK3ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5694119 | 0.78 | PLK1 (0.66) | PLK1PLK3ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013177492-A2 | NOVEL LIPASE INHIBITORS, REPORTER SUBSTRATES AND USES THEREOF | NORTHEASTERN UNIVERSITY (US) | 2013-11-28 | — | — | WO | disclosed |