Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 3/20 | 0.70 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.70 |
| ▸ | ASPH | Q12797 | 4/20 | 0.63 |
| ▸ | KDM8 | Q8N371 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | RIOX2 | Q8IUF8 | 2/20 | 0.63 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.63 |
| ▸ | PLK1 | P53350 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499132 | 0.98 | KDM6B (0.68) | KDM6BKDM4CASPHKDM8KDM4E | |
| SCHEMBL4897624 | 0.95 | KDM6B (0.69) | KDM6BKDM4CASPHKDM8KDM4E | |
| Enfenamic Acid SCHEMBL25191 | 0.88 | KDM6B (0.68) | KDM6BKDM4CASPHKDM8KDM4E | |
| SCHEMBL3514128 | 0.87 | KDM6B (0.59) | KDM6BKDM4CASPHKDM8KDM4E | |
| Enfenamic Acid SCHEMBL10935569 | 0.87 | KDM6B (0.66) | KDM6BKDM4CASPHKDM8KDM4E | |
| SCHEMBL15295175 | 0.83 | KDM4C (1.00) | KDM6BKDM4CASPHKDM8KDM4E | |
| SCHEMBL8689214 | 0.82 | ALDH1A1 (0.79) | KDM6BKDM4CKDM4EPLK1ALDH1A1 | |
| SCHEMBL466141 | 0.82 | PLK1 (0.63) | KDM6BKDM4CKDM4EPLK1ALDH1A1 | |
| SCHEMBL5510920 | 0.82 | ALDH1A1 (0.78) | KDM6BKDM4CKDM4EPLK1ALDH1A1 | |
| SCHEMBL10697917 | 0.82 | ALDH1A1 (0.63) | KDM6BKDM4CASPHKDM8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772198-B2 | CFTR channel modulators | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-08-10 | — | — | US | disclosed |
| US-7772198-B2 | CFTR channel modulators | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-08-10 | — | — | US | disclosed |