⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373679 | 0.80 | PKM (0.34) | — | |
| SCHEMBL1374239 | 0.79 | PKM (0.32) | — | |
| SCHEMBL14759675 | 0.67 | KDM1A (0.45) | — | |
| SCHEMBL14759678 | 0.67 | KDM1A (0.45) | — | |
| SCHEMBL84834 | 0.67 | — | — | |
| SCHEMBL21741426 | 0.67 | — | — | |
| SCHEMBL3722291 | 0.67 | — | — | |
| SCHEMBL10372739 | 0.65 | CTSD (0.48) | — | |
| SCHEMBL4844560 | 0.64 | — | — | |
| SCHEMBL12411186 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864338-A2 | 7-OXO-THIAZOLOPYRIDINE CARBONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | Savira Pharmaceuticals GmbH (AT) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013174930-A2 | 7-OXO-THIAZOLOPYRIDINE CARBONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | SAVIRA PHARMACEUTICALS GMBH (AT) | 2013-11-28 | — | — | WO | disclosed |