SCHEMBL15536397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15535653	0.89	AR (0.38)	ARKDM4ERAB9AALDH1A1
	SCHEMBL15548579	0.86	KDM4E (0.38)	ARKDM4EDUSP3RAB9AALDH1A1
	SCHEMBL15548971	0.86	AR (0.40)	ARPPARAIDH1CYP3A4PPARD
	SCHEMBL15535175	0.85	AR (0.42)	ARKDM4EMAPTRAB9AALDH1A1
	SCHEMBL15534840	0.85	MAPK1 (0.36)	ARKDM4EMAPTRAB9AALDH1A1
	SCHEMBL16969056	0.85	MAOB (0.42)	ARCYP2D6VKORC1ALDH1A1
	SCHEMBL15535215	0.84	NPC1 (0.49)	KDM4EGCGRRAB9AALDH1A1
	SCHEMBL15534789	0.84	KDM4E (0.43)	ARKDM4ECYP1A2CYP3A4CYP2D6
	SCHEMBL15535145	0.84	VKORC1 (0.39)	ARRORCIDH1VKORC1
	SCHEMBL15535172	0.82	ERN1 (0.41)	ARGCGRRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.