Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.36 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61834 | 0.94 | USP2 (0.37) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL60823 | 0.91 | USP2 (0.35) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL15255243 | 0.91 | USP2 (0.37) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL61330 | 0.91 | USP2 (0.37) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL9928006 | 0.90 | USP2 (0.39) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL9927994 | 0.89 | USP2 (0.38) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL15582572 | 0.88 | LMNA (0.40) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL15536159 | 0.88 | USP2 (0.35) | KDM4EMAPK1TDP1USP2HTT | |
| SCHEMBL16306570 | 0.88 | LMNA (0.45) | USP2HTTLPAR5HSF1SPHK1 | |
| SCHEMBL15535483 | 0.87 | KDM4E (0.41) | KDM4EMAPK1TDP1USP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852625-B1 | SILANE GROUPS CONTAINING POLYMER | SIKA TECH AG (CH) | 2019-01-23 | — | — | EP | disclosed |
| US-9714316-B2 | Polymer containing silane groups | SIKA TECHNOLOGY AG (CH) | 2017-07-25 | — | — | US | disclosed |
| US-20150133603-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2015-05-14 | — | — | US | disclosed |
| EP-2852625-A1 | POLYMER CONTAINING SILANE GROUPS | Sika Technology AG (CH) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174892-A1 | POLYMER CONTAINING SILANE GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133603-A1 | POLYMER CONTAINING SILANE GROUPS | HSPH1, EHMT2, EHMT1 | KDM4E 601/4885MAPK1 3521/4885TDP1 3679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.