Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 11/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 11/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538390 | 0.86 | GPR119 (0.77) | GPR119CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL15538381 | 0.81 | TDP1 (0.49) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL16803727 | 0.80 | GPR119 (0.49) | GPR119CYP4F2CYP4A11GPR183 | |
| SCHEMBL15537906 | 0.79 | GPR119 (0.48) | GPR119CYP4F2CYP4A11GPR183 | |
| SCHEMBL15538722 | 0.79 | GPR119 (0.52) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL18842724 | 0.79 | GPR119 (0.56) | GPR119CYP4F2CYP4A11GPR183 | |
| SCHEMBL15539945 | 0.78 | GPR119 (0.54) | GPR119CYP4F2CYP4A11GPR183 | |
| SCHEMBL3982355 | 0.78 | GPR119 (0.77) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL16757789 | 0.77 | GPR119 (0.46) | GPR119CYP4F2CYP4A11 | |
| SCHEMBL15539170 | 0.76 | GPR119 (0.55) | GPR119CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |