Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.46 |
| ▸ | HPGDS | O60760 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538406 | 0.94 | GPR119 (0.51) | GPR119CYP4F2CYP4A11HPGDSDRD2 | |
| SCHEMBL16757926 | 0.93 | GPR119 (0.53) | GPR119CYP4F2CYP4A11HPGDSDRD2 | |
| SCHEMBL15539367 | 0.91 | GPR119 (0.53) | GPR119CYP4F2CYP4A11HPGDSDRD2 | |
| SCHEMBL15539945 | 0.90 | GPR119 (0.54) | GPR119CYP4F2CYP4A11HPGDSSMN1; SMN2 | |
| SCHEMBL16758063 | 0.89 | GPR119 (0.51) | GPR119CYP4F2CYP4A11HPGDSDRD2 | |
| SCHEMBL15538973 | 0.89 | DRD2 (0.48) | DRD2DRD4MAPT | |
| SCHEMBL20053619 | 0.87 | GPR119 (0.60) | GPR119CYP4F2CYP4A11HPGDS | |
| SCHEMBL15539013 | 0.87 | HPGDS (0.42) | GPR119HPGDSDRD2DRD4 | |
| SCHEMBL15540430 | 0.87 | GPR119 (0.44) | GPR119CYP4F2CYP4A11HPGDSDRD2 | |
| SCHEMBL15539134 | 0.87 | GPR119 (0.50) | GPR119CYP4F2CYP4A11HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |
| US-20150166480-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2015-06-18 | — | — | US | disclosed |
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166480-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | GPR119, FFAR2, GPR84 | GPR119 1/4885CYP4F2 2315/4885CYP4A11 1770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.