Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.43 |
| ▸ | LPL | P06858 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12069299 | 0.89 | ROCK1 (0.46) | ARLIPGLPLROCK1BACE1 | |
| SCHEMBL15539398 | 0.85 | ROCK1 (0.43) | LIPGLPLROCK1BACE1BACE2 | |
| SCHEMBL2031833 | 0.84 | F11 (0.39) | LIPGLPLROCK1F11F2 | |
| SCHEMBL1721526 | 0.84 | LIPG (0.46) | LIPGLPLROCK1BACE1BACE2 | |
| SCHEMBL26334393 | 0.84 | LIPG (0.46) | LIPGLPLROCK1BACE1BACE2 | |
| SCHEMBL24274793 | 0.82 | LIPG (0.45) | LIPGLPLROCK1BACE1BACE2 | |
| SCHEMBL15995371 | 0.82 | F11 (0.46) | LIPGLPLROCK1BACE1BACE2 | |
| SCHEMBL30416445 | 0.82 | F11 (0.46) | LIPGLPLROCK1BACE1BACE2 | |
| SCHEMBL3491328 | 0.82 | F11 (0.40) | LIPGLPLROCK1F11F2 | |
| SCHEMBL29897650 | 0.81 | HSP90AA1 (0.43) | LIPGLPLROCK1F11F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858990-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| EP-2858982-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | AbbVie Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013185284-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBOTT LABORATORIES (US) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013188381-A1 | PYRIDINONE AND PYRIDAZINONE DERIVATIVES | ABBVIE INC. (US) | 2013-12-19 | — | — | WO | disclosed |