SCHEMBL1553853

SCHEMBL1553853

CC(CCBr)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.57
TAAR1 Q96RJ0 3/20 0.54
TRPA1 O75762 4/20 0.48
AOC3 Q16853 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3618081 0.86 RIPK1 (0.53) RIPK1TAAR1TRPA1AOC3
SCHEMBL6280516 0.85 RIPK1 (0.67) RIPK1TAAR1TRPA1AOC3
SCHEMBL5213988 0.82 RIPK1 (0.64) RIPK1TAAR1TRPA1AOC3
Lithium SCHEMBL30777534 0.82 RIPK1 (0.64) RIPK1TAAR1TRPA1AOC3
SCHEMBL8159872 0.80 TAAR1 (0.58) RIPK1TAAR1TRPA1AOC3
SCHEMBL583097 0.80 TAAR1 (0.58) RIPK1TAAR1TRPA1AOC3
SCHEMBL2736634 0.80 TAAR1 (0.58) RIPK1TAAR1TRPA1AOC3
SCHEMBL14658424 0.79 ACHE (0.46) RIPK1
SCHEMBL17451533 0.79 RIPK1 (0.55) RIPK1TAAR1TRPA1AOC3
SCHEMBL7041633 0.79 RIPK1 (0.55) RIPK1TAAR1TRPA1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109854-A1 CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
EP-4508101-B1 PROCESS FOR MANUFACTURING OF POLYISOBUTENE SUCCINIC ANHYDRIDES BASF SE (DE) 2026-03-25 EP disclosed
EP-4709518-A1 PROCESS FOR THE PREPARATION OF POLYISOBUTENE FROM OLEFINS FROM ISOBUTANOL OBTAINED FROM MIXED GUERBET REACTION OF ETHANOL AND METHANOL BASF SE (DE) 2026-03-18 EP disclosed
EP-4667447-A1 PROCESS FOR THE PREPARATION OF POLYISOBUTENE FROM BIO-BASED OLEFINS FROM PRIMARY ALCOHOL BASF SE (DE) 2025-12-24 EP disclosed
US-20250250382-A1 PROCESS FOR MANUFACTURING OF POLYISOBUTENE SUCCINIC ANHYDRIDES BASF SE (DE) 2025-08-07 US disclosed
US-20250250403-A1 PROCESS FOR MANUFACTURING OF POLYISOBUTENE SUCCINIC ANHYDRIDES BASF SE (DE) 2025-08-07 US disclosed
US-20250179224-A1 MEDIUM MOLECULAR POLYISOBUTENE WITH A CERTAIN DISTRIBUTION OF DOUBLE BOND ISOMERS BASF SE (DE) 2025-06-05 US disclosed
US-20250145742-A1 MEDIUM MOLECULAR POLYISOBUTENE WITH A HIGH CONTENT OF CERTAIN DOUBLE BOND ISOMERS BASF SE (DE) 2025-05-08 US disclosed
WO-2025082909-A1 PROCESS FOR IMPROVING THE STABILITY OF POLYISOBUTENES BASF SE (DE) 2025-04-24 WO disclosed
US-6800645-B1 INHIBIT PRODUCTION OR PHYSIOLOGICAL EFFECTS OF TNF, INHIBIT CYCLIC AMP PHOSPHODIESTERASE AVENTIS PHARMA LIMITED (GB) 2004-10-05 US disclosed
US-20020173527-A1 Substituted azabicyclic compounds ASTLES PETER CHARLES (GB) 2002-11-21 US disclosed
US-6303600-B1 USED IN THERAPY OF DISEASE STATES ASSOCIATED WITH PROTEINS THAT MEDIATE CELLULAR ACTIVITY RHONE-POULENC RORER LIMITED (GB) 2001-10-16 US disclosed
EP-0934307-A1 SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE RHONE-POULENC RORER LIMITED (GB) 1999-08-11 EP disclosed
WO-1998005327-A1 SUBSTITUTED AROMATIC COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-02-12 WO disclosed
WO-1997048697-A1 SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE RHONE-POULENC RORER LIMITED (GB) 1997-12-24 WO disclosed
US-5262420-A Phenylalkylpyridines IDEMITSU KOSAN CO., LTD. (JP) 1993-11-16 US disclosed
US-4987132-A PLATELET ACTIVATING FACTOR ANTAGONISTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1991-01-22 US disclosed
CN-1030415-A Saturated heterocycle carboxamide derivatives and its preparation method YAMANOUCHI PHARMA CO LTD (JP) 1989-01-18 CN disclosed
EP-0279681-A2 Saturated heterocyclic carboxamide derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109854-A1 CURABLE RESIN COMPOSITION, AND CURED PRODUCT THEREOF MLLT1, CRBN, POT1 RIPK1 1464/4885TAAR1 4109/4885TRPA1 909/4885
US-20020173527-A1 Substituted azabicyclic compounds CBR1, NOX1, POR RIPK1 3390/4885TAAR1 661/4885TRPA1 4125/4885
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME PSMA1, PSMB10, RAD51 RIPK1 1996/4885TAAR1 3193/4885TRPA1 1271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.