Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538376 | 0.86 | AOC2 (0.48) | AOC2MAOBEPHX2TACR3GPR119 | |
| SCHEMBL15537989 | 0.85 | AOC2 (0.47) | AOC2MAOBEPHX2TACR3GPR119 | |
| SCHEMBL15538794 | 0.83 | AOC2 (0.54) | AOC2MAOBGPR119 | |
| SCHEMBL15539682 | 0.83 | AOC2 (0.53) | AOC2MAOBEPHX2TACR3GPR119 | |
| SCHEMBL15538151 | 0.82 | AOC2 (0.54) | AOC2MAOBGPR119 | |
| SCHEMBL15539234 | 0.81 | GPR119 (0.44) | AOC2MAOBGPR119 | |
| SCHEMBL15539948 | 0.80 | AOC2 (0.45) | AOC2MAOBEPHX2TACR3GPR119 | |
| SCHEMBL15537767 | 0.79 | AOC2 (0.58) | AOC2MAOBEPHX2GPR119 | |
| SCHEMBL15539038 | 0.79 | AOC2 (0.57) | AOC2MAOBEPHX2GPR119 | |
| SCHEMBL15538620 | 0.77 | AOC2 (0.47) | AOC2MAOBEPHX2TACR3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |