Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30857688 | 0.94 | PTGS2 (0.41) | PTGS2PTGS1BCL2L1SLC6A3SLC6A2 | |
| SCHEMBL19839271 | 0.85 | PTGS2 (0.39) | PTGS2PTGS1BCL2L1SLC6A3SLC6A2 | |
| SCHEMBL25254777 | 0.81 | PTGS2 (0.43) | PTGS2PTGS1BCL2L1SLC6A3BCL2 | |
| SCHEMBL1701048 | 0.80 | BCL2L1 (0.37) | PTGS2PTGS1BCL2L1SLC6A3SLC6A2 | |
| SCHEMBL1113744 | 0.80 | BCL2L1 (0.52) | PTGS2PTGS1BCL2L1SLC6A3SLC6A2 | |
| SCHEMBL33529723 | 0.78 | BCL2L1 (0.40) | PTGS2PTGS1BCL2L1SLC6A3LMNA | |
| SCHEMBL22325185 | 0.78 | BCL2L1 (0.40) | PTGS2PTGS1BCL2L1SLC6A3LMNA | |
| SCHEMBL24261125 | 0.76 | PTGS2 (0.42) | PTGS2PTGS1BCL2L1SLC6A3SLC6A2 | |
| SCHEMBL1742816 | 0.75 | SLC6A3 (0.46) | PTGS2PTGS1SLC6A3SLC6A2NOTUM | |
| SCHEMBL1957330 | 0.75 | SLC6A3 (0.46) | PTGS2PTGS1SLC6A3SLC6A2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013185202-A1 | APOPTOSIS INDUCERS | BETA PHARMA CANADA INC (CA) | 2013-12-19 | — | — | WO | disclosed |