Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701049 | 0.84 | PTGS2 (0.37) | PTGS2PTGS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL15539299 | 0.79 | PTGS2 (0.44) | PTGS2PTGS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL1497714 | 0.78 | PTGS2 (0.44) | PTGS2PTGS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL1701070 | 0.77 | PTGS2 (0.35) | PTGS2PTGS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL1812781 | 0.77 | PTGS2 (0.39) | PTGS2PTGS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL15540176 | 0.75 | — | — | |
| SCHEMBL1956774 | 0.74 | PTGS2 (0.38) | PTGS2PTGS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL25249186 | 0.74 | PTGS2 (0.40) | PTGS2PTGS1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL1701087 | 0.73 | PTGS2 (0.38) | PTGS2PTGS1HSD17B10 | |
| SCHEMBL1700854 | 0.70 | SLC6A3 (0.37) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013185202-A1 | APOPTOSIS INDUCERS | BETA PHARMA CANADA INC (CA) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013185202-A1 | APOPTOSIS INDUCERS | BETA PHARMA CANADA INC (CA) | 2013-12-19 | — | — | WO | disclosed |