SCHEMBL1553929

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1553677	0.86	ADORA1 (0.69)	ADORA1ADORA2AADORA2B
	SCHEMBL6134194	0.81	ADORA1 (0.43)	ADORA1ADORA2AADORA2BUSP2ALDH1A1
	SCHEMBL1553887	0.81	ADORA2A (0.53)	ADORA1ADORA2AADORA2B
	SCHEMBL3836360	0.79	ADORA2B (0.45)	ADORA1ADORA2AADORA2BALDH1A1
	SCHEMBL5455467	0.77	ADORA1 (0.64)	ADORA1ADORA2AADORA2BRPS6KA3DHFR
	SCHEMBL1554448	0.77	ADORA1 (0.52)	ADORA1ADORA2AADORA2BRPS6KA3
	SCHEMBL6134132	0.76	ADORA1 (0.41)	ADORA1ADORA2AADORA2BUSP2ALDH1A1
	SCHEMBL1553233	0.76	ADORA2A (0.62)	ADORA1ADORA2AADORA2BUSP2ALDH1A1
	SCHEMBL1553927	0.76	ADORA2A (1.00)	ADORA1ADORA2AADORA2BUSP2ALDH1A1
	SCHEMBL1554437	0.76	ADORA1 (0.57)	ADORA1ADORA2AADORA2BRPS6KA3DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.