Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2598198 | 0.78 | BDKRB1 (0.47) | BDKRB1ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL31722799 | 0.78 | BDKRB1 (0.47) | BDKRB1ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL4939408 | 0.75 | LTB4R2 (0.41) | PTPN1GPR119BDKRB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9197575 | 0.74 | L3MBTL1 (0.42) | PTPN1BDKRB1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4265981 | 0.74 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9192373 | 0.73 | MME (0.38) | PTPN1BDKRB1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1421011 | 0.73 | ATR (0.52) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30063181 | 0.73 | ATR (0.52) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL2598199 | 0.73 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2SLC6A3SLC6A4MAPT | |
| SCHEMBL3976878 | 0.72 | ALDH1A1 (0.46) | BDKRB1ALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013186792-A2 | PROCESS FOR THE PREPARATION OF (5-METHYL-2-OXO-L,3-DIOXOI-4-VL)METHVL 2- ETHOXV-L-{[2'-(5-OXO-4,5-DIHVDRO-L,2,4-OXADIAZOL-3-VL)BIPHENYI-4-VL]METHYL}- LH-BENZIMIDAZOLE-7-CARBOXYIATE AND ITS SALTS | MSN LABORATORIES LIMITED (IN) | 2013-12-19 | — | — | WO | disclosed |