SCHEMBL15539615

SCHEMBL15539615

C[C@](O)(C(=O)O)[C@@H](O)c1c(Cl)cccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 6/20 0.38
PDK2 Q15119 6/20 0.38
PDK3 Q15120 6/20 0.38
PDK4 Q16654 6/20 0.38
TSHR P16473 1/20 0.36
AKR1B1 P15121 1/20 0.36
ALOX15 P16050 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CXCL8 P10145 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17093287 1.00 PDK1 (0.38) PDK1PDK2PDK3PDK4TSHR
SCHEMBL28369060 1.00 PDK1 (0.38) PDK1PDK2PDK3PDK4TSHR
SCHEMBL29015077 1.00 PDK1 (0.38) PDK1PDK2PDK3PDK4TSHR
SCHEMBL15538970 0.81 ADRB2 (0.45) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL28368711 0.81 ADRB2 (0.45) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL15540082 0.81 ADRB2 (0.45) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL16795808 0.81 ADRB2 (0.45) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL28364834 0.81 ADRB2 (0.45) PDK1PDK2PDK3PDK4ALDH1A1
SCHEMBL17669972 0.81 CYP2D6 (0.38) PDK1PDK2PDK3PDK4TSHR
SCHEMBL15540563 0.78 AKR1B1 (0.37) TSHRAKR1B1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861571-A1 PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME Bio-Pharm Solutions Co., Ltd. (KR) 2015-04-22 EP disclosed
WO-2013187727-A1 PHENYLALKYL SULFAMATE COMPOUND AND MUSCLE RELAXANT COMPOSITION COMPRISING THE SAME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-12-19 WO disclosed