Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996026 | 0.92 | CA12 (0.41) | KDM4EGAAGLAALDH1A1POLB | |
| SCHEMBL668901 | 0.92 | CA12 (0.41) | KDM4EGAAGLAALDH1A1POLB | |
| SCHEMBL15541454 | 0.83 | KMT2A (0.51) | KDM4EGAAGLAALDH1A1POLB | |
| SCHEMBL9938274 | 0.81 | ELANE (0.38) | ALDH1A1CA12CA9TDP1CA2 | |
| SCHEMBL9938614 | 0.79 | MEN1 (0.42) | CA2KMT2A | |
| SCHEMBL9938547 | 0.79 | KDM4E (0.40) | KDM4EGAAGLAALDH1A1MAPT | |
| SCHEMBL19253296 | 0.77 | NCEH1 (0.30) | MAPTHTTKMT2A | |
| SCHEMBL26104675 | 0.77 | MEN1 (0.30) | MAPTHTTKMT2A | |
| SCHEMBL14644345 | 0.77 | KMT2A (0.39) | KDM4EGAAGLAALDH1A1CA12 | |
| Hydrochloric Acid SCHEMBL23199797 | 0.76 | CA2 (0.34) | CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013188792-A2 | NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF | SAGE THERAPEUTICS, INC. (US) | 2013-12-19 | — | — | WO | disclosed |