Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP8 | P40818 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540862 | 0.80 | MAPT (0.64) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL3435121 | 0.80 | USP8 (0.47) | DRD2MEN1KMT2AUSP8USP7 | |
| SCHEMBL3275743 | 0.78 | MEN1 (0.59) | MEN1KMT2AUSP8USP7MAPT | |
| SCHEMBL520175 | 0.77 | DRD2 (0.62) | DRD2DRD3MEN1KMT2AMAPT | |
| SCHEMBL521120 | 0.76 | DRD2 (0.46) | DRD2DRD3MEN1KMT2AMAPT | |
| SCHEMBL521121 | 0.76 | DRD2 (0.46) | DRD2DRD3MEN1KMT2AMAPT | |
| SCHEMBL5479404 | 0.76 | S100B (0.59) | MEN1KMT2AUSP8USP7MAPT | |
| SCHEMBL16440197 | 0.76 | MEN1 (0.55) | DRD2DRD3MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL23043605 | 0.75 | KDM4E (0.58) | MEN1KMT2AMAPTL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL29977996 | 0.75 | KDM4E (0.58) | MEN1KMT2AMAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013188856-A1 | IMIDAZOPYRAZINE SYK INHIBITORS | GILEAD CONNECTICUT, INC. (US) | 2013-12-19 | — | — | WO | disclosed |