Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28348830 | 0.87 | HPGD (0.50) | HPGDMAPK8PARP14PARP10CTSD | |
| SCHEMBL3728595 | 0.85 | GAA (0.53) | CYP2C9HIF1AMAPK8PARP14PARP10 | |
| SCHEMBL3091346 | 0.84 | KMT2A (0.54) | HPGDMAPK8PARP14PARP10KDM4E | |
| SCHEMBL5685628 | 0.84 | HTR7 (0.52) | HPGDKDM4ELMNAHTTIRAK4 | |
| SCHEMBL7134588 | 0.84 | TSHR (0.54) | HPGDCYP2C9HIF1AKDM4EALDH1A1 | |
| SCHEMBL582321 | 0.81 | CA2 (0.54) | CYP2C9HIF1AALDH1A1LMNAHTT | |
| SCHEMBL7866112 | 0.80 | KDM4E (0.50) | CYP2C9HIF1APARP14PARP10KDM4E | |
| SCHEMBL264288 | 0.80 | IRAK4 (0.63) | HPGDCTSDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29423358 | 0.80 | IRAK4 (0.63) | HPGDCTSDALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3296809 | 0.80 | IDO1 (0.61) | ALDH1A1LMNASMN1; SMN2IDO1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861561-A2 | AMIDOPHENOXYPROPANOLAMINES | Medizinische Universität Wien (AT) | 2015-04-22 | — | — | EP | disclosed |
| WO-2013186153-A2 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2013-12-19 | — | — | WO | disclosed |