Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541138 | 1.00 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15541558 | 1.00 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15540981 | 1.00 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15540979 | 1.00 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15541559 | 1.00 | GPR119 (0.66) | GPR119 | |
| SCHEMBL14244471 | 0.93 | GPR119 (0.65) | GPR119 | |
| SCHEMBL14244470 | 0.93 | GPR119 (0.65) | GPR119 | |
| SCHEMBL9937255 | 0.87 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15007864 | 0.87 | GPR119 (0.66) | GPR119 | |
| SCHEMBL9936725 | 0.87 | GPR119 (0.66) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858996-B1 | 4-(2,3-Dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid ester derivatives as G-protein-coupled receptor 119 (GPR119) agonists for the treatment of metabolic disorders, such as diabetes, dyslipidemia and obesity | BOEHRINGER INGELHEIM INT (DE) | 2016-12-07 | — | — | EP | claimed |
| EP-2858996-A1 | 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2015-04-15 | — | — | EP | claimed |
| WO-2013186109-A1 | 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-19 | — | — | WO | claimed |
| EP-2858996-B1 | 4-(2,3-Dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid ester derivatives as G-protein-coupled receptor 119 (GPR119) agonists for the treatment of metabolic disorders, such as diabetes, dyslipidemia and obesity | BOEHRINGER INGELHEIM INT (DE) | 2016-12-07 | — | — | EP | disclosed |
| EP-2858996-B1 | 4-(2,3-Dihydro-furo[2,3-c]pyridin-2-yl)-piperidine-1-carboxylic acid ester derivatives as G-protein-coupled receptor 119 (GPR119) agonists for the treatment of metabolic disorders, such as diabetes, dyslipidemia and obesity | BOEHRINGER INGELHEIM INT (DE) | 2016-12-07 | — | — | EP | disclosed |
| EP-2858996-A1 | 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2015-04-15 | — | — | EP | disclosed |
| US-8975277-B2 | 2,3-dihydrofuro[2,3-c]pyridin-2-ylpiperidine derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-03-10 | — | — | US | disclosed |
| US-8975277-B2 | 2,3-dihydrofuro[2,3-c]pyridin-2-ylpiperidine derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-03-10 | — | — | US | disclosed |
| WO-2013186109-A1 | 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-19 | — | — | WO | disclosed |
| WO-2013186109-A1 | 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-12-19 | — | — | WO | disclosed |