SCHEMBL15540979

SCHEMBL15540979

CC(OC(=O)N1CCC([C@]2(C)Cc3cc(C4=CCN(S(C)(=O)=O)CC4)ncc3O2)CC1)C(F)(F)F

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15541138 1.00 GPR119 (0.66) GPR119
SCHEMBL15541558 1.00 GPR119 (0.66) GPR119
SCHEMBL15540977 1.00 GPR119 (0.66) GPR119
SCHEMBL15540981 1.00 GPR119 (0.66) GPR119
SCHEMBL15541559 1.00 GPR119 (0.66) GPR119
SCHEMBL14244471 0.93 GPR119 (0.65) GPR119
SCHEMBL14244470 0.93 GPR119 (0.65) GPR119
SCHEMBL9937255 0.87 GPR119 (0.66) GPR119
SCHEMBL15007864 0.87 GPR119 (0.66) GPR119
SCHEMBL9936725 0.87 GPR119 (0.66) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2858996-A1 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF Boehringer Ingelheim International GmbH (DE) 2015-04-15 EP claimed
WO-2013186109-A1 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-12-19 WO claimed
EP-2858996-A1 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF Boehringer Ingelheim International GmbH (DE) 2015-04-15 EP disclosed
WO-2013186109-A1 2,3-DIHYDRO-FURO[2,3-C]PYRIDIN-2-YL-PIPERIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USES THEREOF BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-12-19 WO disclosed