Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862986 | 0.83 | — | — | |
| SCHEMBL16111098 | 0.82 | NCF1 (0.47) | NCF1MAPTNAMPTKDM1AMAOB | |
| SCHEMBL8136269 | 0.80 | MTNR1A (0.45) | NCF1MAPTNAMPTEPHX1EPHX2 | |
| SCHEMBL13301082 | 0.77 | EPHX1 (0.50) | MAPTEPHX1EPHX2TDP1 | |
| SCHEMBL16494745 | 0.76 | CYP2D6 (0.50) | NCF1MAPTNAMPTKDM1AMAOB | |
| SCHEMBL23173065 | 0.74 | MAPT (0.43) | NCF1MAPTNAMPTKDM1AMAOB | |
| SCHEMBL13621194 | 0.74 | TDP1 (0.67) | NCF1MAPTNAMPTPARP1EPHX1 | |
| SCHEMBL10205595 | 0.74 | NCF1 (0.47) | NCF1MAPTNAMPTKDM1AMAOB | |
| SCHEMBL13853539 | 0.73 | MAPT (0.48) | NCF1MAPTNAMPTEPHX1EPHX2 | |
| SCHEMBL12935918 | 0.73 | CKS1B (0.45) | NCF1MAPTNAMPTHDAC4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864309-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | Cadila Healthcare Limited (IN) | 2015-04-29 | — | — | EP | claimed |
| WO-2014002105-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2014-01-03 | — | — | WO | claimed |