SCHEMBL1554442

SCHEMBL1554442

CC(C)(O)C(=O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.56
SRD5A2 P31213 4/20 0.55
PDK1 Q15118 1/20 0.49
PDK2 Q15119 1/20 0.49
PDK3 Q15120 1/20 0.49
PDK4 Q16654 1/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
KMT2A Q03164 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
POLB P06746 1/20 0.49
HSP90AA1 P07900 1/20 0.49
ERCC5 P28715 1/20 0.49
FEN1 P39748 1/20 0.49
HPGD P15428 2/20 0.48
MAPT P10636 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10941467 0.95 SRD5A2 (0.64) PARP10SRD5A2PDK1PDK2PDK3
SCHEMBL195348 0.92 HPGD (0.56) PARP10SRD5A2RAB9ASMN1; SMN2ALDH1A1
SCHEMBL29206740 0.91 SRD5A2 (0.59) PARP10SRD5A2POLBPPARA
Formaldehyde SCHEMBL28801121 0.89 HPGD (0.52) PARP10SRD5A2RAB9ASMN1; SMN2ALDH1A1
SCHEMBL24799711 0.87 PARP10 (0.58) PARP10SRD5A2RAB9ASMN1; SMN2NPC1
SCHEMBL8357803 0.87 PARP10 (0.58) PARP10SRD5A2RAB9ASMN1; SMN2NPC1
SCHEMBL17263293 0.87 ELANE (0.50) PARP10SRD5A2RAB9ASMN1; SMN2NPC1
SCHEMBL3691895 0.86 PARP10 (0.57) PARP10RAB9ASMN1; SMN2NPC1POLB
SCHEMBL29592795 0.85 POLB (0.46) PARP10SRD5A2PDK1PDK2PDK3
SCHEMBL31393464 0.85 PARP10 (0.56) PARP10RAB9ASMN1; SMN2ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003002-B1 USE OF AROMATIC-ALIPHATIC KETONES AS PHOTOINITIATORS, PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH KETONES AND AROMATIC-ALIPHATIC KETONES CIBA-GEIGY AG (CH) 1984-06-13 EP claimed
EP-0003002-A2 Use of aromatic-aliphatic ketones as photoinitiators, photopolymerisable systems containing such ketones and aromatic-aliphatic ketones CIBA-GEIGY AG (CH) 1979-07-11 EP claimed
CN-113518805-B Photoinitiator 意大利艾坚蒙树脂有限公司 2023-08-08 CN disclosed
CN-113518805-A Photoinitiator 意大利艾坚蒙树脂有限公司 2021-10-19 CN disclosed
EP-1670740-B1 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2011-04-27 EP disclosed
US-7534880-B2 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2009-05-19 US disclosed
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings LAMBERTI SPA (IT) 2006-11-02 US disclosed
EP-1670740-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS Lamberti Spa (IT) 2006-06-21 EP disclosed
WO-2005014515-A2 CLEAR PHOTOPOLYMERIZABLE SYSTEMS FOR THE PREPARATION OF HIGH THICKNESS COATINGS LAMBERTI SPA (IT) 2005-02-17 WO disclosed
US-4960746-A A-HYDROXY-OR A-AMINO-ACETOPHENONES AND A TITANOCENE COMPOUND SUBSTITUTED BY FLUORINE CIBA-GEIGY CORPORATION (US) 1990-10-02 US disclosed
EP-0146501-B1 POLYMERIZABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1988-03-16 EP disclosed
US-4518676-A Photopolymerizable compositions containing diaryliodosyl salts CIBA GEIGY CORPORATION (US) 1985-05-21 US disclosed
EP-0104143-A1 Photopolymerizable compositions containing diaryliodosyl salts CIBA-GEIGY AG (CH) 1984-03-28 EP disclosed
EP-0094914-A2 Photopolymerisation with organometal salts CIBA-GEIGY AG (CH) 1983-11-23 EP disclosed
US-4351708-A A COCATALYST MIXTURE OF AN AROMATIC IODONIUM SALT, AN AROMATIC CARBONYL PHOTOINITIATOR AND A FREE RADICAL CATALYST CIBA-GEIGY CORPORATION (US) 1982-09-28 US disclosed
US-4321118-A Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition CIBA-GEIGY CORPORATION (US) 1982-03-23 US disclosed
US-4318791-A PHOTOPOLYMERIZABLE SYSTEM FOR INKS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4315807-A Sensitizers for photopolymerization CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4308400-A AROMATIC HYDROXY KETONES CIBA-GEIGY A.G. (CH) 1981-12-29 US disclosed
US-4284485-A STABILIZED WITH A POLYALKYLPIPERIDINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060246228-A1 Clear photopolymerizable systems for the preparation of high thickness coatings CDH1, CLTA, VCL PARP10 1908/4885SRD5A2 4185/4885PDK1 4824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.