Sugi Predict

Sugi Predict / Compounds / SCHEMBL8357803

SCHEMBL8357803

SCHEMBL8357803

CC(C)(C)C(=O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PARP10 Q53GL7 1/20 0.58
▸ SRD5A2 P31213 4/20 0.56
▸ RAB9A P51151 3/20 0.54
▸ NPC1 O15118 2/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ MEN1 O00255 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.50
▸ ELANE P08246 2/20 0.50
▸ HPGD P15428 2/20 0.50
▸ ERCC5 P28715 1/20 0.50
▸ FEN1 P39748 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ HSP90AA1 P07900 1/20 0.50
▸ PPARA Q07869 1/20 0.49
▸ PGR P06401 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24799711 1.00 PARP10 (0.58) PARP10SRD5A2RAB9ANPC1ALDH1A1
SCHEMBL20612798 0.95 SRD5A2 (0.66) PARP10SRD5A2RAB9ANPC1ALDH1A1
SCHEMBL24813408 0.92 HPGD (0.58) PARP10SRD5A2RAB9ANPC1ALDH1A1
SCHEMBL1553905 0.87 PARP10 (0.56) PARP10SRD5A2RAB9ANPC1ALDH1A1
SCHEMBL1554442 0.87 PARP10 (0.56) PARP10SRD5A2RAB9ANPC1ALDH1A1
SCHEMBL17263293 0.85 ELANE (0.50) PARP10SRD5A2RAB9ANPC1ALDH1A1
SCHEMBL11528364 0.85 MMP13 (0.58) PARP10RAB9AALDH1A1LMNAKMT2A
SCHEMBL11529955 0.85 PARP10 (0.61) PARP10RAB9AALDH1A1LMNAELANE
SCHEMBL26054651 0.84 AKR1C3 (0.66) PARP10RAB9ANPC1ALDH1A1LMNA
SCHEMBL14044621 0.83 MAPT (0.53) SRD5A2RAB9ANPC1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3962459-A Lipidemia treatment with p-phenoxy-alkylphenone compositions SANDOZ, INC. (US) 1976-06-08 — — US claimed
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 — — US disclosed
WO-2021085321-A1 RESIN COMPOSITION, RESIN SHEET, CURED FILM, METHOD FOR MANUFACTURING CURED FILM, SEMICONDUCTOR DEVICE, ORGANIC EL DISPLAY DEVICE, AND DISPLAY DEVICE 東レ株式会社 2021-05-06 — — WO disclosed
US-10905679-B2 TRPM8 receptor agonist compounds and uses thereof UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE (ES) 2021-02-02 — — US disclosed
US-20200361994-A1 PEPTIDE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 — — US disclosed
US-20190022068-A1 TRPM8 RECEPTOR AGONIST COMPOUNDS AND USES THEREOF UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE (ES) 2019-01-24 — — US disclosed
US-20120316105-A1 Polymyxin Derivates Useful As Antibacterial Agents PFIZER INC. 2012-12-13 — — US disclosed
US-20120316105-A1 Polymyxin Derivates Useful As Antibacterial Agents PFIZER INC. 2012-12-13 — — US disclosed
US-7956196-B2 the major cause of lower respiratory tract illness during infancy and childhood TIBOTEC PHARMACEUTICALS LTD. (IE) 2011-06-07 — — US disclosed
US-20080146564-A1 1,3-Dihydro-Benzimidazol-2-Ylidene Amines as Inhibitors of Respiratory Syncytial Virus Replication JANSSEN SCIENCES IRELAND UC (IE) 2008-06-19 — — US disclosed
US-4085149-A HYPOLIPIDEMIC SANDOZ, INC. (US) 1978-04-18 — — US disclosed
US-4085149-A HYPOLIPIDEMIC SANDOZ, INC. (US) 1978-04-18 — — US disclosed
US-4065503-A HYPOLIPIDEMIC AGENTS SANDOZ, INC. (US) 1977-12-27 — — US disclosed
US-4065503-A HYPOLIPIDEMIC AGENTS SANDOZ, INC. (US) 1977-12-27 — — US disclosed
US-4008327-A ANTIDIABETIC SANDOZ, INC. (US) 1977-02-15 — — US disclosed
US-3997567-A HYPOLIPIDEMIC SANDOZ, INC. (US) 1976-12-14 — — US disclosed
US-3985883-A ANTI-OBESITY AGENTS SANDOZ, INC. (US) 1976-10-12 — — US disclosed
US-3962459-A Lipidemia treatment with p-phenoxy-alkylphenone compositions SANDOZ, INC. (US) 1976-06-08 — — US disclosed
US-3962459-A Lipidemia treatment with p-phenoxy-alkylphenone compositions SANDOZ, INC. (US) 1976-06-08 — — US disclosed
US-3946119-A Optionally substituted α-tertiary butyl-p-phenoxybenzylamines and their use as hypolipidemic agents SANDOZ, INC. (US) 1976-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080146564-A1 1,3-Dihydro-Benzimidazol-2-Ylidene Amines as Inhibitors of Respiratory Syncytial Virus Replication H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, RTF2 PARP10 760/4885SRD5A2 1085/4885RAB9A 606/4885
US-20190022068-A1 TRPM8 RECEPTOR AGONIST COMPOUNDS AND USES THEREOF TRPM8, TRPM7, TRPM5 PARP10 2692/4885SRD5A2 1450/4885RAB9A 1547/4885
US-10905679-B2 TRPM8 receptor agonist compounds and uses thereof TRPM8, TRPM7, TRPM5 PARP10 2692/4885SRD5A2 1450/4885RAB9A 1547/4885
US-20200361994-A1 PEPTIDE ANTIBIOTICS NGLY1, VIP, PEPD PARP10 1445/4885SRD5A2 4761/4885RAB9A 1956/4885
US-11279733-B2 Peptide antibiotics NGLY1, VIP, PEPD PARP10 1445/4885SRD5A2 4761/4885RAB9A 1956/4885
US-20120316105-A1 Polymyxin Derivates Useful As Antibacterial Agents NPEPPS, MDN1, PNKP PARP10 598/4885SRD5A2 4777/4885RAB9A 3754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.