Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677887 | 0.88 | L3MBTL1 (0.63) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL25009812 | 0.85 | L3MBTL1 (0.76) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL30556174 | 0.85 | L3MBTL1 (0.76) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL11395284 | 0.84 | L3MBTL1 (0.61) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL382067 | 0.83 | L3MBTL1 (0.82) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL21243071 | 0.82 | LMNA (0.82) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL25009811 | 0.82 | L3MBTL1 (0.82) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL5353549 | 0.81 | L3MBTL1 (0.70) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL28859518 | 0.81 | L3MBTL1 (0.80) | L3MBTL1LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL5363062 | 0.81 | L3MBTL1 (0.70) | L3MBTL1LMNAALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885307-A1 | 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | Actelion Pharmaceuticals Ltd. (CH) | 2015-06-24 | — | — | EP | claimed |
| CN-104428305-A | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2015-03-18 | — | — | CN | claimed |
| WO-2014006585-A1 | 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2014-01-09 | — | — | WO | claimed |
| CN-104428305-A | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin d2 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2015-03-18 | — | — | CN | disclosed |