Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.45 |
| ▸ | FASN | P49327 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544411 | 0.86 | SIGMAR1 (0.52) | SIGMAR1OPRM1FASNKCNH2CHRM2 | |
| SCHEMBL23015954 | 0.81 | SIGMAR1 (0.52) | SIGMAR1OPRM1FASNCHRM2CHRM3 | |
| SCHEMBL15544468 | 0.81 | FASN (0.42) | SIGMAR1OPRM1FASNKCNH2CHRM2 | |
| SCHEMBL23015964 | 0.81 | SIGMAR1 (0.67) | SIGMAR1OPRM1FASNKCNH2CHRM2 | |
| SCHEMBL15544787 | 0.80 | SIGMAR1 (0.44) | SIGMAR1OPRM1FASNKCNH2CHRM2 | |
| SCHEMBL15543949 | 0.80 | SIGMAR1 (0.47) | SIGMAR1OPRM1FASNKCNH2CHRM2 | |
| SCHEMBL15544532 | 0.80 | SIGMAR1 (0.44) | SIGMAR1OPRM1FASNKCNH2CHRM2 | |
| SCHEMBL23015951 | 0.80 | FASN (0.53) | SIGMAR1OPRM1FASN | |
| SCHEMBL4540317 | 0.78 | FASN (0.61) | FASN | |
| SCHEMBL15543473 | 0.78 | FASN (0.43) | SIGMAR1OPRM1FASNKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014008223-A2 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2014-01-09 | — | — | WO | disclosed |